Todd C. McDevitt, PhD

Biography

Todd C. McDevitt, PhD

Email:  todd.mcdevitt@bme.gatech.edu

Todd C. McDevitt, Ph.D., graduated with a Bachelor of Science in Engineering (BSE) from Duke University in 1997 after double majoring in Biomedical Engineering and Electrical Engineering.Todd received his Ph.D. in Bioengineering from the University of Washington in 2001. He completed his dissertation research in the laboratory of Patrick Stayton, Ph.D., working on protein engineering and micropatterning techniques to spatially control cell assembly for cardiac and skeletal muscle tissue engineering. In 2001, Todd joined Chuck Murry's lab in the Department of Pathology as a post-doctoral fellow. His post-doctoral research focused on signaling pathways mediating proliferation of cardiomyocytes derived from stem cells for the purpose of myocardial repair.

In August of 2004, Todd joined the faculty in the Wallace H. Coulter Department of Biomedical Engineering at the Georgia Institute of Technology / Emory University. In 2009 he was appointed as a Petit Faculty Fellow in the Parker H. Petit Institute for Bioengineering and Bioscience and was named as the Director of the Stem Cell Engineering Center at Georgia Tech.

The McDevitt laboratory is focused on the development of engineering approaches to translate the potential of stem cells into viable regenerative therapies and in vitro diagnostics.

McDevitt is a young leader aiming to help define the new burgeoning field of “stem cell engineering” via a combination of research, education and policy efforts. His scholarly activities at the interface of biomaterials, tissue engineering and stem cell research have been recognized by receipt of the 2010 Young Investigator Award from the Society for Biomaterials, election to the North American council for the Tissue Engineering and Regenerative Medicine International Society (TERMIS-NA), and one of 30 U.S. scientists age 45 and under to be invited to participate in the Frontiers of Engineering symposia series hosted by the National Academy of Engineering.

McDevitt is PI of the $3 million NSF Integrated Graduate Education and Research Training (IGERT) program on Stem Cell Biomanufacturing which was highlighted in Nature as an "out-of-the-box" novel graduate training program. In addition, Todd was recently appointed to a six-member panel of North American experts by the National Science Foundation to a conduct an international assessment of stem cell engineering research and development efforts that is intended to inform strategic investments by the U.S. in this emerging area of biotechnology.

The McDevitt lab has been examining the use of human mesenchymal stromal/stem cells (MSCs) to modulate inflammation/immunological signaling. They have done this through the use of pre-conditioning regimens intended to enhance the immunomodulatory secretory properties of MSCs prior to transplantation and are beginning to use inflammation and auto-immune mouse models to test the feasibility and efficacy of our proposed strategies.